Desarrollo de un juego como herramienta multimedia de aprendizaje y evaluación / Development of a game as a learning and Evaluation method

El empleo de recursos multimedia fomenta la curiosidad científica y apoya y refuerza el proceso deaprendizaje y evaluación. Necesitamos fomentar la capacidad del alumno para trabajar en equipo ycompartir conocimientos y su participación en el desarrollo de la práctica docente. En este sentido ungrupo de profesores de la Universidad de Granada estamos diseñando un programa de software libre,basado en un juego didáctico, el trivial, que sirva de herramienta multimedia para el aprendizaje y laevaluación del alumno. El sistema permite al profesor definir la composición de los equipos y las partidasque éstos pueden jugar.Este proyecto está financiado por la Unidad de Innovación Docente de la Universidad de Granada y está deacuerdo con la política de utilización de software libre de la UGR. Asimismo, de acuerdo con dicha política,estamos valorando liberar el software desarrollado(AU)

The use of multimedia tools improves scientific curiosity, provides support and reinforces the process oflearning and evaluation at the classroom. It is very important to estimulate some student’s skills as theircapacity to working in group, their ability of to share knowledgement as well as their participation throughthe process of the teaching-learning process. According to the above mentioned issues, a team of proffesorsat the University of Granada are developping a free software based tool. The software, inspired in thepopular game “Trivial PursuitTM” would help as a multimedia tool for the learning and evaluation of thestudent. The system allows the teacher to define team composition and the games to be played(AU)

Loss of a reporter gene for green fluorescent protein during tumor progression suggests the recruitment of host cells in rats with experimentally induced colon cancer.

The interactions between a host's normal cells and tumor cells appear to be of significant importance during the development of tumors. In the present study, we examined this issue using a cancer model in vivo in which tumor cells were tagged with a reporter gene for green fluorescent protein (GFP). We used a model of colon cancer in immunocompetent rats, which were given a subcutaneous injection of tumor cells that had been transfected with a gene for GFP. We found that the number of fluorescent cells decreased with the progression of the primary tumors and that lymph node and lung metastases were never macroscopically fluorescent. No GFP-encoding sequences were detected by PCR in many of the long-term primary tumors, in most lymph node metastases (86%) and in all lung metastases, whereas the detection of mutated k-ras, which identified such cells as tumor cells, was always positive. To explain these findings, we present a brief review of the literature and postulate that tumor growth did not occur exclusively as a result of the division of the injected cells, but also involved recruitment of host cells.